What is IUI? A Simple Guide for First-Timers

If you have been trying to conceive without success, chances are, you’ve come across the term IUI. It’s one of the most common and less invasive fertility treatments, and for many, it’s the first step on the assisted reproduction journey.

At Womb IVF and Fertility, we understand how overwhelming fertility treatment options can seem, especially when you’re just getting started. That’s why we’ve put together this simple, easy-to-understand guide to IUI (Intrauterine Insemination) for first-timers.

So, what is IUI?

IUI, or Intrauterine Insemination, is a fertility treatment where specially prepared sperm is directly inserted into a woman’s uterus during ovulation to improve the chances of fertilization.

The goal is simple: bring sperm closer to the egg and increase the likelihood of conception. It’s often recommended for couples facing mild infertility issues or for individuals who are using donor sperm.

Who Can Benefit from IUI?

IUI is generally a good option for:

  • Women with unexplained infertility
  • Men with mild male factor infertility (such as low sperm count or motility)
  • Women with cervical mucus issues
  • Individuals or couples using donor sperm
  • Same-sex couples
  • Women with ovulation disorders like PCOS (when ovulation can be induced)

Note: IUI may not be effective for women with blocked fallopian tubes or severe endometriosis. In such cases, IVF (In-Vitro Fertilization) is usually recommended.

How Does the IUI Procedure Work?

Here’s what the IUI process looks like at Womb IVF and Fertility:

  1. Ovulation Monitoring

Your ovulation cycle is tracked using blood tests and ultrasounds. Sometimes, ovulation induction medication (like Clomid or Letrozole) may be prescribed to stimulate egg production.

  1. Semen Collection and Preparation

Semen is collected from your partner or donor. It is then “washed” in the lab to remove impurities and select the healthiest, most motile sperm.

  1. IUI Procedure

At the time of ovulation, the prepared sperm is inserted directly into the uterus using a thin, flexible catheter. The procedure is quick, painless, and takes just a few minutes.

  1. Post-Procedure

You can return to your normal routine the same day. A pregnancy test is usually done about two weeks later.

Is IUI Painful?

Not at all. Most people compare the IUI procedure to a routine Pap smear. You might feel mild cramping or discomfort, but it’s generally quick and minimally invasive.

What Are the Success Rates of IUI?

Success rates can vary based on age, diagnosis, and individual health. On average:

Women under 35: 10–20% success rate per cycle

Women 35–40: 10–15% success rate

Women over 40: 5–10% success rate

Fertility medications, multiple cycles, and timing accuracy can significantly improve the chances.

IUI vs IVF: What’s the Difference?

AspectIUIIVF
InvasivenessMinimally invasiveMore invasive
ProcedureSperm inserted into uterusEgg and sperm fertilized in lab
CostMore affordableMore expensive
Success RateLower than IVFHigher success rate
Suitable ForMild infertility issuesSevere infertility, older age

Is IUI Right for You?

The best way to find out is through a personalized consultation. At Womb IVF and Fertility, we perform a detailed fertility assessment, including:

Hormone testing

Semen analysis

Pelvic ultrasound

Ovulation tracking

Based on your results, we guide you on whether IUI is the best treatment path or if alternatives like IVF, ICSI, or egg freezing might be more suitable.

IUI is often a hopeful first step for many on their path to parenthood. It’s less invasive, affordable, and for the right candidate, highly effective. If you’re exploring your fertility options and wondering if IUI is right for you, we’re here to walk that path with you—honestly, gently, and professionally.

At Womb IVF and Fertility, we believe in demystifying fertility care and offering personalized, science-backed solutions with compassion.

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